BDNF immunohistochemistry in the cerebral cortex reveals a pattern of expression similar to that observed for BDNF mRNA after striatal excitotoxic lesions. A, B,C, Immunolocalization of BDNF protein in the prefrontal cortex ipsilateral to PBS-, QUIN-, or KA-injected striata, respectively. D, E, F, Detailed photomicrographs of prefrontal layer V after injection of PBS, QUIN, or KA in the striatum, respectively. Scale bars:A–C, 200 μm; D–F, 100 μm.