Skip to main content
. 2001 Jan 1;21(1):45–52. doi: 10.1523/JNEUROSCI.21-01-00045.2001

Fig. 6.

Fig. 6.

Parallel effects of the Egr inhibitor construct in blocking neurite outgrowth and ERE-mediated transcription by NGF.A, The amount of Egr inhibitor plasmid used for transfection was varied from 0 to 1000 ng/well. To keep the total amount of transfected DNA constant, we added appropriate amounts of pCB6 plasmid. The bar graph presents the increase in luciferase activity detected in cell extracts harvested 6–8 hr after treatment with NGF. B, The effect of varying the amount of Egr inhibitor plasmid on the percentage of cells scored as neurite bearing after NGF exposure is presented in this bar graph. In the absence of NGF, 9 ± 6% (mean ± SEM) of cells were scored as bearing neurites.