Skip to main content
. 2001 Apr 15;21(8):2610–2621. doi: 10.1523/JNEUROSCI.21-08-02610.2001

Table 3.

Simulation of Process S assuming a linear buildup rate

τi (%/hr) τd(hr) DIF2 r
AK 27.1 (2.0) 2.1 (0.2) 386 (48) 0.92
C 18.8 (2.2) 1.8 (0.2) 273 (57) 0.90
B6 15.0 (1.3) 2.2 (0.1) 221 (31) 0.90
Br 21.1 (2.9) 1.6 (0.2) 412 (99) 0.92
D2 10.5 (0.9) 2.1 (0.3) 326 (97) 0.86
129 18.9 (2.0) 1.7 (0.1) 336 (66) 0.88
p <0.0001 0.2 0.5 0.5

The simulation of Process S was repeated with the assumption of a linear buildup. The decrease still followed an exponential decline with the same lower asymptotes (Table 1). Significant genotype differences were observed for the buildup rate [τi; mean (SEM); Tukey's range test: AK = Br > Br = 129 = C = B6 > C = B6 = D2; p < 0.05; n = 7 per strain]. The minimum square of the differences (DIF2) did not differ between the two approaches (two-way ANOVA with repeated measures: factor linear vs exponential: p = 0.3; factor strain: p = 0.3; interaction: p = 0.9; n = 7 per strain). The average difference in DIF2was 27 ± 22 %2 (linear − exponential; n = 42). p values underneath each column indicate results from a one-way ANOVA with factor strain.