Fig. 2.
Coexpression of GluR1flip and GluR1flip (L497Y) gives an intermediate component of decay.Aa, Current elicited by 5 mm glutamate (bar) in a patch from a cell transiently cotransfected with equal amounts of wild-type GluR1flip and the GluR1flip (L497Y) mutant. The decay of the current contains three resolvable exponential components. The triple exponential fit (smooth solid line) and the corresponding residual current (res) are shown. Ab, The same current and the fit are shown on an expanded time scale, together with each of the individual exponential components (dotted lines). The three components decay at fast (f; τf = 3.72 msec), intermediate (i; τi = 19.5 msec), and slow (s; τs = 97 msec) rates. The slow component of decay and the steady-state plateau current are treated as a single component. Each of the three components represents approximately one-third of the total current.