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. 2001 Aug 1;21(15):5607–5619. doi: 10.1523/JNEUROSCI.21-15-05607.2001

Fig. 9.

Fig. 9.

Electron micrographs of prenatal and postnatal layer I cells with typical morphology of the C–R cells.A, In the visual cortex in the E112 monkey, a large cell with eccentrically positioned nucleus, abundant cytoplasm with parallel rows of rough endoplasmic reticulum, and several thin processes emerging from the cell body (arrow). B, At 7 months of age (P222). Arrows point to axosomatic synapses. C, In a 4-year-old monkey, cells with C–R morphology. Inset, The endoplasmic reticulum at higher magnification. Cisterns of endoplasmic reticulum at this age are scattered around the soma. D, E, Examples of two C–R-like cells at 10 years of age. A tangential cut through layer I is shown. Inset, At higher magnification, the breaking of parallel rows of rough endoplasmic reticulum. F, A large subpial C–R cell visualized on a 1 μm Nissl-stained section of the motor cortex in a 20-year-old monkey. Scale bars: A, 2.5 μm; B, 1 μm; C–E, 5 μm;F, 30 μm.