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Molecular and morphological patterning defects in a Hoxa1 mutant hindbrain. A dorsal view of 11.5 dpc WT (A, C) andHoxa1−/− (B, D) mutant hindbrains hybridized with the r4-specific Hoxb1(A, B) or carrying a lacZ reporter under the control of an r2-specific enhancer (C, D) is shown.Vertical arrows indicate the location of the motoneuron progenitor columns.
