Fig. 2.

Spontaneous horizontal locomotor activity in a novel cage (first trial, A and C) and habituation to repeated exposures (third trial, B andD) to the same environment in drug and handling naïve GluR-A subunit-deficient mouse lines and their wild-type controls. The mouse line codes (with the number of animals) are shown. Both mutant lines had higher activity than the wild-type controls, which can be seen in E, depicting the total activity scores. Repeated trials demonstrated that all of the lines habituated to the test environment, but still on the third trial the mutants exhibited higher activity than their controls. Pointsand bars indicate means ± SEM. *p < 0.05 for the difference from the corresponding activity of the control line; #p < 0.05 for the difference between the trials within a line; Duncan's test.