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. 2001 Jun 15;21(12):4451–4459. doi: 10.1523/JNEUROSCI.21-12-04451.2001

Fig. 4.

Fig. 4.

Tail-flick latencies in GluR-A subunit-deficient mouse lines and their wild-type controls in drug-free (A) and morphine-affected states (B, C). A, Tail-flick latencies of the initial baseline trial and the trials 30 and 60 min after the injection of saline (Sal; 10 ml/kg, s.c.).B, C, Percentage of the maximal possible effect (%MPE) at 30 and 60 min after saline or morphine (Mor; 5 mg/kg) injections in GluR-A−/− and wild-type control mice (B) and in GluR-A(R/R) and their control mice (C) before the chronic treatment and 15 hr after the last injection of 8 d of chronic morphine treatment with escalating doses (Chr). Thebars indicate means ± SEM. *p < 0.05 for the difference from the corresponding acute morphine value; #p < 0.05 for the difference from the corresponding control mouse line; Duncan's test.