Table 1.

Aβ 1–40 and Aβ 1–42 levels in the cerebral cortex, hippocampus, and cerebellum of Tg and WT littermates at different ages

	Age (months)	Cortex		Hippocampus		Cerebellum
		Aβ 1–40 (pmol/g)	Aβ 1–42 (pmol/g)	Aβ 1–40 (pmol/g)	Aβ 1–42 (pmol/g)	Aβ 1–40 (pmol/g)	Aβ 1–42 (pmol/g)
Tg	4	23  ± 17	42  ± 16	173  ± 23	179  ± 18	133  ± 22	156  ± 24
	8	39  ± 25	52  ± 25	179  ± 23	221  ± 36	159  ± 24	148  ± 26
	12	5041  ± 688	2353  ± 706	1688  ± 89	1221  ± 53	520  ± 205	622  ± 185
	15	7840  ± 1413	3910  ± 706	4365  ± 580	2024  ± 497	628  ± 307	700  ± 299
	18	19,181  ± 2437	5646  ± 718	13,604  ± 1317	4784  ± 263	1030  ± 180	1034  ± 161
WT	4	<5	<5	<5	<5	<5	<5
	8	<5	<5	<5	<5	<5	<5
	12	<5	<5	<5	<5	<5	<5
	15	11  ± 3	9  ± 3	11.5  ± 3	12  ± 4	10  ± 3	9  ± 2
	18	11  ± 3	9.6  ± 3	9  ± 2	9  ± 2	11  ± 2	10  ± 3

Results are expressed as mean ± SEM. Cortex, Cerebral cortex.