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Suppression of cortical NMDA receptor function from P21 to P49 prevented maturation of stimulus size selectivity in cortical neurons. A, Example of a peristimulus time histogram from an antisense-ODN treated cortical neuron shows responses to a large stationary stimulus. B, Example from an untreated neuron illustrates lack of responses to large stimuli in most cells from normal animals. C, Pooled results (mean and SE).
