Fig. 5.
Intraplantar injection of capsaicin induces bursting discharge in nociceptors. A, Instantaneous frequency plot of burst discharge of a heat-sensitive C nociceptor in response to subdermal injection of 100 μg/100 μl capsaicin (CAPS; rectangleindicates the duration of the injection). B, Response of the same unit as in A to repeated heating to 47.6°C (bottom trace indicates the temperature ramp).C, A different type of bursting discharge in another heat-sensitive C nociceptor evoked by subdermal injection of 100 μg/100 μl capsaicin (first rectangleindicates the duration of the injection). D, Detail of period of discharge indicated by second(bold) rectangle inC.