Fig. 6.

Reduction in the percentage of cells with topographically correct projections with inhibition of NO synthesis. Fluorescent micrographs show all cells in the ganglion cell layer stained with DAPI (blue) and cells retrogradely labeled (red) from an injection of microspheres in the contralateral tectum. The micrographs show the area of the retinas with the highest density of retrogradely labeled cells. Retinas were from embryos treated with 2 μmol of l-NoArg (A) or saline (B) during the period of refinement. Scale bar, 25 μm. C, A lower percentage of cells were retrogradely labeled after inhibition of NO synthesis (p = 0.002). Error bars indicate SE.