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Survival analysis of sod2nullizygous mice treated with synthetic catalytic antioxidants. Kaplan–Meier survival analysis demonstrates enhanced survival ofsod2 nullizygous mice treated with EUK-8, EUK-134, or EUK-189 (30 mg/kg) versus untreated sod2 nullizygous mice. MnTBAP was administered at the limiting dose of 5 mg/kg as described previously (Melov et al., 1998).
