Reinstatement of food-seeking behavior is blocked by inhibition of the VP but not the dPFC or NAcore. Pretreatment with the screening dose of bac–mus (0.3 and 0.03 nmol/side, respectively) into the VP inhibited lever-press responding elicited by noncontingent food presentation, whereas infusion of bac–mus into the NAcore or PFC (0.3 and 0.03 nmol/side, respectively) resulted in response rates indistinguishable from saline (SAL) pretreatment (i.e., a robust reinstatement). *p < 0.001, comparing food reinstatement responding with extinction (EXT) responding.