Fig. 5.
Effects of Nav1.8 antisense ODN on TTX-resistant sodium currents in bladder afferent neurons.A, Superimposed traces of TTX-resistant sodium currents elicited by depolarizing pulses to 10 mV from the holding potential of −60 mV in neurons from rats treated with mismatch and antisense ODN.B, Maximum conductance densities of TTX-resistant sodium currents. In rats treated with antisense ODN, the conductance density of TTX-resistant sodium currents (n = 15 neurons) was significantly smaller compared with rats with mismatch ODN treatment (n = 15 neurons). *p< 0.05.