Skip to main content
. 2001 Jul 15;21(14):5045–5053. doi: 10.1523/JNEUROSCI.21-14-05045.2001

Fig. 3.

Fig. 3.

Time course of p16INK4adownregulation and delayed neuronal death after 30 min MCAo.A, The number of p16INK4a-negative and MAP-2 positive cells is presented as a percentage of all MAP-2-positive cells at 9, 18, 48, and 72 hr after MCAo as well as in sham-operated, control mice. In controls and at 72 hr after MCAo, all MAP-2-positive cells were also p16INK4apositive. B, The number of TUNEL-positive cells per square millimeters was determined at the same time points as inA. No TUNEL positivity was observed in sham-operated animals and at 9 hr after MCAo, whereas the maximum number of TUNEL-positive cells was observed at 72 hr after MCAo;n = 3–6. Data are mean values ± SEM. *p < 0.05; ***p < 0.001.