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. 2001 Jul 15;21(14):5110–5120. doi: 10.1523/JNEUROSCI.21-14-05110.2001

Fig. 6.

Fig. 6.

3-NP enhances basal and NMDA-induced intracellular calcium concentration in striatal spiny neurons. The histogram shows the mean percentage of increase ± SEM of intracellular calcium (expressed as ratio values) in response to NMDA, 3-NP alone, and NMDA in the presence of 3-NP (a). Thetraces in the top panel show the membrane depolarization induced by NMDA (30 μm) in the control condition (left) and after 20 min of 3-NP treatment (right). The bottom panel shows the simultaneous measurements of intracellular calcium levels in the same neuron (b). Resting membrane potential = −84 mV. *p < 0.05; **p < 0.01; ***p < 0.001 (Student's ttest for paired observations).