Table 1.

Effect of receptor agonists on membrane potential of dopamine neurons

Drug	Before	During drug	Change	p value	Number
Dopamine (4 or 10 μm)	−54.9  ± 1.0	−60.1  ± 1.6	−5.2*	<0.001	17
DA + D2antagonist	−54.8  ± 2.3	−53.9  ± 2.1	0.9	0.47	6
Baclofen (10 μm)	−57.8  ± 3.2	−76.9  ± 3.2	−19.1*	<0.001	7
Orphanin FQ (1 μm)	−56.1  ± 2.5	−74.6  ± 1.9	−18.6*	<0.001	9

Membrane potential (in mV) of dopamine neurons during and a comparable period just before the application of drugs is presented as mean ± SEM.

^*denotes a statistically significant change in voltage analyzed with a paired Student's t test. The p value and number of cells used for each drug are shown in the last two columns.