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. 2001 Oct 1;21(19):7831–7840. doi: 10.1523/JNEUROSCI.21-19-07831.2001

Fig. 4.

Fig. 4.

The effect of sensitization and intra-accumbens amphetamine on lever pressing during each successive CS+ versus CS− cue presented over the course of the test sessions. Aand B depict lever pressing in the sensitized and control rats after a microinjection of intra-accumbens vehicle. For sensitized rats, more lever pressing was triggered by the sucrose CS+ than by its paired CS− (two-way ANOVA; *p < 0.01; Bonferroni), and there was a tendency for the sucrose CS+ to evoke more presses in the control rats, but this difference was not statistically significant. C and D depict lever pressing in both rat groups after a microinjection of intra-accumbens amphetamine. Intra-accumbens amphetamine boosted sucrose cue-elicited lever pressing in control rats to a level that was comparable with the cue-elicited performance of drug-free sensitized rats, and under the amphetamine microinjection both rat groups engaged in significantly more pressing elicited by the sucrose CS+ than by its paired CS− (two-way ANOVAs; *p < 0.05; Bonferroni).