. 2001 Oct 1;21(19):7630–7641. doi: 10.1523/JNEUROSCI.21-19-07630.2001

Table 2.

Comparison of ganglion volume, neuronal number, and neuronal soma volume of cochlear ganglia

		Ganglion volume^2-a(mm³)		Number of neurons^2-b (in thousands)		Neuronal soma^2-c volume (μm³)
		Mean	% variation^2-d	Mean	% variation^2-d	Mean	% variation^2-d
P5
Igf-1^+/+	n = 3	0.046 ± 0.009	0	16.1 ± 0.7	0	506 ± 42	0
Igf-1^−/−	n = 3	0.051 ± 0.010	+11	16.8 ± 0.2	4	527 ± 23	+4
P20
Igf-1^+/+	n = 5	0.048 ± 0.003	+4	16.6 ± 0.6	3	547 ± 28	+8
Igf-1^+/−	n = 3	0.043 ± 0.003^2-e	−6	17.6 ± 0.6	9	482 ± 29^2-e	−5
Igf-1^−/−	n = 5	0.035 ± 0.003^2-f,^2-g	−24	13.4 ± 0.9^2-f,^2-g	−17	380 ± 15^2-f,^2-g	−25

All data were obtained using stereological methods as described in Materials and Methods and are expressed as mean ± SD.

^F2-a

The total volume of ganglia (mm³ ± SD) represents regions occupied by neuronal cell bodies and excludes areas containing nerve fibers. Data were obtained applying the principle of Cavalieri.

^F2-b

The number of neurons in the cochlear ganglion was estimated by means of the “optical fractionator.”

^F2-c

Neuronal soma volume (μm³ ± SD) was obtained using the “rotator.”

^F2-d

Percentual variation with respect to P5 Igf-1^+/+.

^F2-e

Differs from P20Igf-l^+/+; p < 0.05.

^F2-f

Differs from P20Igf-1^+/+; p < 0.001.

^F2-g

Differs from P5Igf-1^−/−; p < 0.005.