Fig. 8.
Effects of l-NAME on pathological changes in the small intestine of CD−/− mice.A–C, The small intestine from control littermate at P24 (A), CD−/− mouse at P24 (B), and CD−/− mouse at P24 (C) treated with l-NAME. The treatment of l-NAME markedly ameliorated hemorrhage-necrotic appearance of the small intestine from CD−/− mice. D–F, Longitudinal sections through ileum from control littermate at P24 (D), CD−/− mouse at P24 (E), and CD−/− mouse at P24 (F) treated with l-NAME. The treatment of l-NAME markedly ameliorated atrophic changes of the ileal mucosa of CD−/− mice. Scale bars: A, 5 mm; D, 100 μm.