Skip to main content
. 2001 Mar 1;21(5):1787–1794. doi: 10.1523/JNEUROSCI.21-05-01787.2001

Fig. 2.

Fig. 2.

Entrained circadian rhythms of wheel-running activity in wild-type (DAT +/+) and homozygous DAT knock-out (DAT −/−) mice. Representative raster plots (top 2 panels) show nocturnal consolidation of wheel-running and a lack of wheel-running activity during the light phase in both DAT +/+ and DAT −/− mice. Group mean ± SEM waveforms are shown for DAT +/+ (filled triangles; n = 7), DAT −/− (filled circles; n= 6), and heterozygous DAT +/− (open squares;n = 4) mice in the bottom panel.Tick marks in the raster plots denote when wheel-running activity was present in 5 min bins. Light–dark bar at the top denotes lighting schedule. Twenty-four hour activity patterns of DAT −/− mice differ significantly from those of DAT +/+ mice (p < 0.02; two-way repeated-measures ANOVA), *p < 0.05; DAT−/− versus DAT +/+; Bonferroni's–Dunn's post hoccomparisons.