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Nicotinic currents in DA neurons of the SN and VTA. A1, ACh (1 mm; 30 msec) elicits currents of similar waveform in the VTA and SN, characterized by a round peak and sigmoid decay. B1, In the same neurons, nicotine (20 μm; 300 msec) elicits much longer lasting currents. A2, Mean ACh-elicited current amplitude in the SN and VTA. B2, Mean nicotine-elicited current amplitude in the SN and VTA. Nicotine induces larger currents in the VTA than in the SN (*p < 0.05).
