Table 4.
Daytime (ZT 5–ZT 7) | Nighttime (ZT 17–ZT 19) | |||||
---|---|---|---|---|---|---|
Control | Sleep deprived | Mann–Whitney p values | Control | Sleep deprived | Mann–Whitney p values | |
n | 7 | 8 | 6 | 6 | ||
Fos-IR neurons | 25 ± 4 | 101 ± 4 | 0.001 | 57 ± 4 | 79 ± 6 | 0.01 |
Orexin-IR neurons | 81 ± 3 | 74 ± 3 | N.S. | 80 ± 3 | 72 ± 5 | N.S. |
Double-labeled neurons | 5 ± 1 | 41 ± 3 | 0.001 | 31 ± 2 | 34 ± 3 | N.S. |
Non-orexin-IR, Fos-IR neurons | 20 ± 4 | 60 ± 4 | 0.001 | 26 ± 3 | 44 ± 5 | 0.007 |
% Wake | 21.2 ± 3.2 | 99.7 ± 0.2 | 0.001 | 89.2 ± 3.5 | 100 ± 0.0 | 0.002 |
% NREM sleep | 62.5 ± 3.3 | 0.1 ± 0.1 | 0.0006 | 9.2 ± 2.9 | 0.0 ± 0.0 | 0.002 |
% REM sleep | 16.3 ± 2.2 | 0.2 ± 0.2 | 0.0006 | 1.0 ± 0.6 | 0.0 ± 0.0 | N.S. |
Tb (°C) | 36.8 ± 0.1 | 37.7 ± 0.1 | 0.001 | 37.9 ± 0.2 | 38.3 ± 0.2 | N.S. |
Change in Tb (°C) | 0.0 ± 0.1 | 0.3 ± 0.1 | 0.03 | 0.0 ± 0.1 | 0.3 ± 0.1 | N.S. |
LMA | 0.4 ± 0.1 | 2.4 ± 0.2 | 0.001 | 2.1 ± 0.1 | 2.7 ± 0.5 | N.S. |