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Caspase 3 is required for apoptosis of the Rb-deficient trigeminal and dorsal root ganglia neurons. Frozen sections from wild type (A–D), caspase 3−/− (E–H), Rb−/− (I–L), and Rb−/−/caspase 3−/− (M–P) were stained for TUNEL and counterstained with PGP 9.5 to view neuronal cell bodies and axons.Panels on left show Trigeminal Ganglion, and panels onright show Rostral DRG. Scale bars, 160 μm.
