Fig. 3.
A, The application of the selective 5-HT2A receptor antagonist M100907 (100 and 300 μm; filled triangles andcircles, n = 8 and 4, respectively) antagonized the increase in 5-HT output induced by the local application of DOI 100 μm. B, Lack of antagonism of the effect of DOI by the selective 5-HT2C receptor antagonist SB 242084 (100 μm;filled circles, n = 6). This drug significantly potentiated the 5-HT increase elicited by DOI (shown by adotted line). +p < 0.05 versus baseline (DOI alone); *p < 0.05 versus DOI alone (DOI + drug); Duncan test post-ANOVA.