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Necrotic cell death of CGCs (PI-positive cells) induced by NO-saturated water or NO donor (NOC-18) after 24 hr of exposure was prevented by NO scavengers PTIO (A) or hemoglobin (B) or by high oxygen (95% O2/5% CO2) (C). The data present the mean ± SD of three independent experiments. *p < 0.05, **p < 0.01 from control groups and+p < 0.05,++p < 0.01 from NO or NOC-18 treatment.
