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Subcellular localization of Bax. Bax expression was analyzed by Western blot in cytosolic (A,B) and mitochondrial (C,D) fractions of spinal cords from transgenic mSOD1 mice (black columns) at the asymptomatic stage (AS), at the beginning of symptoms (BS), and at the end stage (ES) and was compared with their age-matched nontransgenic littermates (Non-Tg; white columns). Represented values (n = 4–6 per group) correspond to mean ± SEM. *p < 0.05; **p < 0.01; Student's t test.
