Estrogen reduces the frequency of mIPSCs in CA1 pyramidal cells at the 241 time point.A, Representative traces from five different 241O cells showing mIPSCs.B, Representative traces from five different 241E cells showing mIPSCs.Arrowheads indicate representative mIPSCs with a prolonged decay time in 241E cells.C, Bar graph of mIPSC frequency in 3DO (gray bar; n = 12 cells from 6 animals), 241O (white bar;n = 18 cells from 10 animals), and 241E (black bar;n = 22 cells from 10 animals) groups. Data are from the same cells shown in Figure 2C. Theasterisk indicates a significant difference from 3DO and 241O (p < 0.05).