At the 482 time point, the mIPSC frequency in estrogen-treated animals has recovered to baseline values and is greater than that in oil-treated controls.A, Representative traces from five different 482O cells showing mIPSCs.B, Representative traces from five different 482E cells showing mIPSCs.C, Bar graph of mIPSC frequency in 3DO (gray bar; n = 12 cells from 6 animals), 482O (white bar;n = 20 cells from 10 animals), and 482E (black bar;n = 22 cells from 10 animals) groups. Data are from the same cells shown in Figure 7. The double asterisksindicate a significant difference from 3DO and 482E (p < 0.01).