Fig. 5.

Kv3.1/Kv3.3-deficient mice are hypersensitive to ethanol. Ethanol (in 0.9% saline) was injected intraperitoneally in male mice, and sideways falls were counted for the first 10 min after ethanol injection [mean ± SEM and number of mice (above eachvertical bar) shown]. The ethanol effect was fully visible within 2 min of injection and lasted for ∼20 and ∼45 min for 1 and 2 mg/gm, respectively.