. 2001 Sep 1;21(17):6657–6665. doi: 10.1523/JNEUROSCI.21-17-06657.2001

Table 1.

Phenotypic traits of Kv3.1/Kv3.3-deficient mice

Genotype	Kv3.1^+/+Kv3.3^+/+	Kv3.1^+/−Kv3.3^+/−	Kv3.1^−/−Kv3.3^−/−
Active avoidance	Normal	Normal	Normal
Ataxia (rotarod)	None	None	*Severe^1-a*
Tremor	None	None	*Present*
Myoclonus	None	None	*Every few seconds*
Ethanol sensitivity	Normal	Normal	*Hypersensitive*
Body weight	100%	88%^1-b	*50%*
Spont. locomotion^1-c	100%	217%	*273%*
Ctr-field occupancy^1-d	100%	*486%*	*439%*

Graded penetrance of phenotypic traits is shown. Depending on the number of mutant alleles (0, 2, or 4), phenotypic traits show different degrees of penetrance and may be classified in four distinct groups.

^F1-a

Full penetrance is shown in bold letters.

^F1-b

Altered phenotypic traits are italicized.

^F1-c

Spont., spontaneous.

^F1-d

Ctr, Center.