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. 2001 Sep 1;21(17):6791–6801. doi: 10.1523/JNEUROSCI.21-17-06791.2001

Fig. 7.

Fig. 7.

Postnatal changes in paired-pulse depression. The effects of PPS applied to the white matter and to layer IV were measured for the first 8 weeks of age. A,B, Comparison of the PPD profiles obtained at two different ages (4 and 6 weeks) with white matter stimulation (A) and layer IV stimulation (B). C, Time course of developmental changes in PPD evoked with WM stimulation. Plotted against postnatal age is the average paired-pulse response ratio obtained with short ISIs (20, 40, 80 msec). The numberof experiments included in the analysis is indicated inparentheses. D, Developmental changes in the magnitude of WM → III LTP. Plotted is the average change in response magnitude recorded 20 min after LTP induction at different postnatal ages [redrawn from Kirkwood et al. (1995)].