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. 2001 Sep 1;21(17):6694–6705. doi: 10.1523/JNEUROSCI.21-17-06694.2001

Table 1.

Pairwise multiple comparison test using Fisher's LSD procedure for differences in CaMKII autonomous activation after electrical stimulation, varying action potential frequency, number, and stimulus duration

Hz 0 1 1 0.1 0.3 0.5 1 3 10 1 3 10 10 1 10
AP 0 5 15 45 45 45 45 45 45 150 150 150 450 600 6000
sec 0 5 15 450 150 90 45 15 4.5 150 50 15 45 600 600
n 32 9 15 13 9 9 21 10 15 3 3 15 15 6 6
% 100 106 147 93 114 131 127 126 128 142 128 164 124 116 104
AP Hz sec n %
0 0 0 32 100 x
5 1 5 9 106 NS x
15 1 15 15 147 * * x
45 0.1 450 13 93 NS NS * x
45 0.3 150 9 114 NS NS * NS x
45 0.5 90 9 131 * NS NS * NS x
45 1 45 21 127 * NS NS * NS NS x
45 3 15 10 126 * NS NS * NS NS NS x
45 10 4.5 15 128 * NS NS * NS NS NS NS x
150 1 150 3 142 * NS NS * NS NS NS NS NS x
150 3 50 3 128 NS NS NS NS NS NS NS NS NS NS x
150 10 15 15 164 * * NS * * * * * * NS NS x
450 10 45 15 124 * NS NS * NS NS NS NS NS NS NS * x
600 1 600 6 116 NS NS NS NS NS NS NS NS NS NS NS * NS x
6000 10 600 6 104 NS NS * NS NS NS NS NS NS NS NS * NS NS x

A subset of these data are plotted against stimulus time in Figure 5A and action potential number in Figure5B; p < 0.0001 by one-way ANOVA;n = 178. %, Autonomous CaMKII activity relative to unstimulated control; Hz, stimulus frequency (action potentials/sec); AP, number of action potentials in stimulus; sec, stimulus duration in seconds; n number of samples (cultures);

*

p < 0.05, pairwise comparison; NS,p > 0.05, pairwise comparison.