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Fractionation of pOFQ/N C-terminal (c-term)-containing peptides in WT and PC-2-deficient mice. Extracts were fractionated as described in Figure 5, and the fractions were assayed for OFQ/N and C-terminal peptide immunoreactivity. The elution positions of synthetic peptides are indicated by the arrows. The dashed lineindicates the percentage of acetonitrile. A, Heterozygote;B, PC null.
