Fig. 4.
DAT immunoreactivity is present in the ENS of SERT +/+ and SERT −/− mice. All four panelsillustrate DAT immunoreactivity. A, Myenteric plexus of the colon of a mouse with a +/+ genotype for both SERT and DAT.B, Myenteric plexus of the colon of a mouse with a −/− genotype for SERT and a +/− genotype for DAT. Thearrows indicate the location of DAT-immunoreactive nerve cell bodies; the arrowheads indicate the location of neurites entering the tertiary plexus. C, Submucosal plexus of the small intestine of a mouse with a +/+ genotype for both SERT and DAT. D, Submucosal plexus of the small intestine of a mouse with a −/− genotype for SERT and a +/+ genotype for DAT.