Table 1.
The expression of Nav1.8 and Nav1.9 within sensory neuronal subtypes in the DRG with increasing development
| Neuronal marker | Age category | % neuronal marker in total cell population | % Nav1.8 in neuronal marker population | % Nav1.9 in neuronal marker population |
|---|---|---|---|---|
| TrkA | E17 | 79.5 (±1.0) | 78.8 (±1.3) | 55.0 (±3.0) |
| P0 | 78.6 (±0.6) | 63.0 (±3.5) | 48.9 (±2.5) | |
| P7 | 60.2 (±3.2) | 51.1 (±2.0) | 43.7 (±2.6) | |
| P21 | 45.3 (±1.8) | 41.8 (±2.6) | 43.4 (±3.5) | |
| Adult | 42.0 | 49.2 (±5.3) | 45.5 (±6.0) | |
| IB4 | E17 | 15.0 (±0.8) | 13.4 (±1.9) | 44.1 (±3.1) |
| P0 | 28.2 (±0.8) | 21.4 (±2.8) | 64.8 (±3.8) | |
| P7 | 42.3 (±1.2) | 31.5 (±1.6) | 60.5 (±1.3) | |
| P21 | 39.3 (±1.2) | 45.2 (±1.8) | 59.9 (±1.7) | |
| Adult | 40.0 | 55.0 (±6.7) | 59.8 (±6.0) | |
| NF200 | E17 | 21.2 (±1.7) | 11.0 (±1.4) | 0.83 (±2.2) |
| P0 | 35.7 (±1.0) | 14.5 (±1.6) | 8.62 (±2.0) | |
| P7 | 42.4 (±1.5) | 12.1 (±2.6) | 6.64 (±1.4) | |
| P21 | 47.0 (±1.9) | 13.0 (±1.8) | 2.64 (±0.5) | |
| Adult | 40.0 | 18.4 (±2.7) | 0 (±0) |
The change in expression of the neuronal markers (TrkA, IB4, and neurofilament NF200) in the DRG during development is represented as a proportion of positive profiles from the total cell profile population. The change in the distribution of Nav1.8 and Nav1.9 expression within each neuronal subtype is represented as a proportion of Nav1.8 and Nav1.9 positive profiles within the total neuronal marker profile population. Each value represents the mean percentage of positive profiles from 10 animals per age category for the % neuronal marker column, and 5 animals per age group for the Nav1.8 and Nav1.9 columns, with the SEM between animals in parentheses.