Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
In vitro metabolic stability, intrinsic clearance in human liver microsomes and plasma protein binding of PTM and PTM-2t.
| Compd. | T1/2(min) | Intrinsic Clearance (μL/min/mg) | Plasma Protein Binding (%) |
|
|---|---|---|---|---|
| Free | Bound | |||
| PTM | 51.0 | 14.0 | 34.0 | 66.0 |
| PTM-2t | 22.0 | 32.0 | 65.0 | 35.0 |
