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. Author manuscript; available in PMC: 2019 Sep 26.
Published in final edited form as: Chem Rev. 2018 Jul 27;118(16):7409–7531. doi: 10.1021/acs.chemrev.7b00678

Figure 2.

Figure 2.

Size scale of cargoes of interest for intracellular delivery. The top left quadrant represents 5 nm. The top right quadrant represents 50 nm, including a pink box showing the scale of the 5 nm quadrant. The bottom right quadrant represents 500 nm, including a green box showing the scale of the 50 nm quadrant. The bottom left quadrant represents 5 μm, including a blue box showing the scale of the 500 nm quadrant. The properties of each of the cargoes and their applications are discussed throughout chapter 2. PBFI is a potassium indicator. ASO: antisense oligonucleotide. siRNA: small interfering RNA. miRNA: micro RNA. GFP: green fluorescent protein. RNP: ribonucleoproteins. TALEN: Transcription activator-like effector nuclease. ZFN: zinc finger nuclease. The pressure sensor is actually 6 μm long but here scaled to half size for presentation purposes.