Figure 8. Deletion of miR-223 impairs alternative activation of hepatic macrophages in SRLI.
(A) Representative FACS analysis of primary hepatic macrophages from mice from the experiment in Figure 4B showing single CD11b-positive (total macrophages) and double Ly6C- and F4/80-positive (proinflammatory macrophages) or CD206- and F4/80-positive (restorative macrophages) cells. Upper quadrants on the CD11b axis and upper right quadrant on the Ly6C and F4/80 or CD206 and F4/80 axis represent the percentage of single-positive or double-positive cells, respectively. (B) Percentage of double Ly6C- and F4/80-positive or CD206- and F4/80-positive cells. *P < 0.05, ***P < 0.001, 2-way ANOVA, n = 3–4. Results are displayed as means ± SD. Representative experiment of 2 repeats.