Figure 6. Association between baseline IgG against Spn and cluster abundance.

(A) Levels of baseline IgG levels against whole-cell 6B Spn in serum are shown for carriage^– (blue, n = 12) and carriage⁺ (red, n = 8) subjects. Box plots depicting median and interquartile ranges, with whiskers extending to 1.5× interquartile range or maximum value, and individual subjects, connected by dashed lines, are shown. (B) Correlation between abundance of clusters and baseline levels of IgG are shown. Individuals subjects and regression lines per group are shown, with 95% confidence intervals depicted in gray. *P = 0.03 determined by linear regression model including carriage status and log-transformed baseline IgG levels.