Table 3.
Histology findings before and after 6 hours of normothermic ex-vivo kidney perfusion (NEVKP) assessed by hematoxylin-eosin. Biopsies scored on a scale of (0–3) and represented as median (range) for 10 high-power fields.
| Criteria | Baseline | p | After 6h NEVKP | p | |||
|---|---|---|---|---|---|---|---|
| HBOC n=7 | PRBC n=7 | HBOC n=7 | PRBC n=7 | ||||
| Tubular dilation | 0.8 (0.1 – 2.4) | 0.5 (0.2–2.2) | 0.23 | 1.1 (0.5 – 2) | 1.4 (1 – 2.1) | 0.17 | |
| Epithelial vacuolization | 0 (0 – 0.8) | 0.1 (0 – 0.6) | 0.53 | 0.5 (0 – 1.3) | 1.6 (1.5 – 2.4) | 0.03 | |
| Epithelial desquamation | 1 (0.9 – 1.7) | 1.2 (0.3 – 1.9) | 0.74 | 1 (0.5 – 1.6) | 1.4 (1 – 2.2) | 0.24 | |
| Coagulation necrosis | 1.1 (0.5 – 1.4) | 1 (0.2 – 1.7) | 0.99 | 1 (0.2 – 1) | 2 (0.9 – 2.5) | 0.01 | |
| Tubular integrity | 1 (0.2 – 1.5) | 1.3 (0.5 – 1.5) | 0.61 | 1.5 (1– 2) | 2.3 (1.8 – 3) | 0.02 | |