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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Genet Epidemiol. 2019 Jun 19;43(7):776–785. doi: 10.1002/gepi.22243

Table 2.

SNP-based (hSNP2)and pedigree-based (h2) heritability estimates for glycemic biomarkers

h2(SOLAR) hSNP2(LDAK) hSNP2(GCTA)

Heritability
(SE)
P-value Heritability
(SD)
P-value Heritability
(SE)
P-value

Fructosamine 0.44 (0.13) 2.9E–04 0.13 (0.06) 0.01 0.11 (0.03) 1.1E–03
Glycated albumin 0.45 (0.13) 1.8E–04 0.30 (0.07) 8.6E–07 0.10 (0.04) 2.5E–03
1,5–AG 0.55 (0.13) 1.3E–05 0.17 (0.06) 3.6E–03 0.15 (0.04) 5.3E–05
HbA1c 0.34 (0.13) 0.01 0.30 (0.07) 2.6E–06 0.17 (0.04) 1.1E–06
Fasting glucose 0.02 (0.03) 0.43 0.08 (0.07) 0.11 0.05 (0.04) 0.08

LDAK N=5,575, relatedness cutoff=0.25; GCTA N=6443, relatedness cutoff=0.05; SOLAR N=400

LDAK inflation <3.3% for all heritability estimates