. Author manuscript; available in PMC: 2020 Dec 1.

Published in final edited form as: J Neuroophthalmol. 2019 Dec;39(4):444–450. doi: 10.1097/WNO.0000000000000768

Table 2.

Comparison of OCT-derived measures between patients with multiple sclerosis and healthy controls.

	HC (eyes = 44)	MS (eyes = 131)	HC vs. MS	HC vs. MS
	Mean, μm (SD)	Mean, μm (SD)	Mean difference, μm	p-value
BMO-MRW	337 (77)	297 (66)	40	0.01
pRNFL – 3.5 mm	105 (11)	88 (17)	17	<0.001
pRNFL – 4.1 mm	90 (8)	75 (13)	14	<0.001
pRNFL – 4.7 mm	78 (7)	67 (11)	11	<0.001
GCIPL	80 (4)	66 (11)	14	<0.001

MS = multiple sclerosis cohort; HC = healthy controls; BMO-MRW = Bruch’s membrane opening minimum rim width; pRNFL = peri-papillary retinal nerve fiber layer; GCIPL = ganglion cell + inner plexiform layer; mm = millimeters; μm = micrometers

p-values were derived from mixed-effect linear regression restrictive maximum likelihood models, accounting for within-subject inter-eye correlation and adjusting for age and sex.

Bolded values designate statistical significance