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. 2019 Sep 26;9:13924. doi: 10.1038/s41598-019-50436-1

Figure 5.

Figure 5

Hypothetical models illustrating how pre-treatment levels of pGSN could predict stage 1 OVCA and RD. (a) Increased pre-operative levels of pGSN at diagnosis could predict high RD in OVCA patients before surgery/treatment while low levels of pGSN at diagnosis could indicate minimal RD after surgery. (b) During the onset of OVCA (stage 1), increased levels of pGSN are detectable in the plasma of patients which could improve survival. However, in advanced stages of OVCA pGSN levels in patients’ plasma decrease, an indication of poor survival.