TABLE 1.
Individual effect analysis.
| Total cohort |
Obesity (n = 1257) |
Hypertension (n = 1127) |
Hyperlipidemia (n = 1036) |
Diabetes mellitus (n = 1257) |
|||||
| Non-OB | OB | Non-HT | HT | Non-HL | HL | Non-DM | DM | ||
| n | 1257 | 886 | 371 | 451 | 676 | 687 | 349 | 1051 | 206 |
| % within groups | 70.5 | 29.5 | 40.0 | 60.0 | 66.3 | 33.7 | 83.6 | 16.4 | |
| Age, sex, CCI | |||||||||
| Average age | 55.7 | 55.4 | 56.3 | 46.2 | 63.8∗ | 56.4 | 54.0∗ | 54.5 | 61.7∗ |
| SD (average age) | 17.0 | 17.7 | 15.2 | 15.2 | 14.1 | 17.8 | 14.5 | 17.3 | 13.9 |
| Male (%) | 57.1 | 59.3 | 52.0 | 61.9 | 51.8 | 55.6 | 64.8∗ | 56.4 | 60.7 |
| Female (%) | 42.9 | 40.7 | 48.0∗ | 38.1 | 48.2∗ | 44.4 | 35.2 | 43.6 | 39.3 |
| Average CCI | 1.4 | 1.3 | 1.6 | 0.9 | 1.7 | 1.3 | 1.7 | 1.0 | 2.9 |
| SD (CCI) | 1.6 | 1.6 | 1.7 | 1.4 | 1.7 | 1.6 | 1.8 | 1.4 | 1.7 |
| Etiology (%) | |||||||||
| Biliary | 37.8 | 33.6 | 47.7∗ | 31.3 | 44.1 | 41.3 | 26.4 | 38.2 | 35.9 |
| Alcoholic | 18.5 | 21.1 | 12.1 | 20.2 | 12.4 | 21.4 | 17.2 | 19.0 | 15.5 |
| HTG-induced | 3.7 | 3.0 | 5.4 | 3.3 | 3.7 | 0.1 | 12.9∗ | 2.8 | 8.7∗ |
| Alcoholic + HTG-induced | 1.8 | 1.9 | 1.6 | 1.6 | 1.9 | 0.0 | 6.6 | 1.8 | 1.9 |
| Post-ERCP | 2.6 | 3.0 | 1.6 | 3.1 | 2.8 | 2.9 | 0.9 | 2.6 | 2.9 |
| Combined | 8.0 | 7.1 | 10.0 | 11.1 | 7.0 | 7.7 | 7.2 | 7.9 | 8.3 |
| Idiopathic | 20.5 | 22.0 | 17.0 | 21.5 | 20.7 | 18.8 | 23.8 | 20.6 | 20.4 |
| Other | 7.1 | 8.1 | 4.6 | 8.0 | 7.4 | 7.7 | 5.2 | 7.2 | 6.3 |
| Severity, mortality, LOS | |||||||||
| Mild (%) | 69.6 | 69.9 | 69.0 | 70.1 | 69.5 | 73.5 | 64.2∗ | 69.7 | 68.9 |
| Moderate (%) | 25.1 | 26.1 | 22.6 | 26.8 | 23.4 | 22.1 | 29.5 | 24.9 | 25.7 |
| Severe (%) | 5.3 | 4.1 | 8.4∗ | 3.1 | 7.1∗ | 4.4 | 6.3 | 5.3 | 5.3 |
| Mortality (%) | 2.4 | 2.1 | 3.0 | 1.3 | 3.1 | 2.3 | 1.4 | 2.5 | 1.9 |
| Average LOS | 10.9 | 10.4 | 12.1∗ | 10.5 | 11.8∗ | 10.5 | 11.4 | 10.7 | 11.8 |
| SD (LOS) | 9.3 | 8.6 | 10.6 | 7.9 | 10.1 | 9.0 | 10.3 | 9.0 | 10.6 |
| Complications (%) | |||||||||
| Local complications | 29.0 | 28.6 | 30.2 | 29.5 | 28.3 | 25.3 | 34.7∗ | 29.1 | 28.6 |
| Fluid collection | 25.0 | 24.7 | 26.7 | 23.9 | 25.3 | 22.1 | 29.8∗ | 24.9 | 27.2 |
| Pseudocyst | 7.6 | 7.8 | 7.3 | 6.9 | 9.3 | 6.0 | 10.6∗ | 7.6 | 7.8 |
| Necrosis | 8.0 | 7.1 | 10.2 | 7.8 | 8.0 | 8.2 | 8.9 | 8.3 | 6.8 |
| New onset diabetes | 3.8 | 3.5 | 4.6 | 2.7 | 4.1 | 3.6 | 5.2 | 4.6 | N/A |
| Systemic complications | 7.6 | 6.0 | 11.3∗ | 3.8 | 10.1∗ | 6.6 | 9.5 | 7.0 | 10.2 |
| Respiratory failure | 4.6 | 3.5 | 7.3∗ | 2.0 | 6.1∗ | 4.5 | 4.9 | 4.1 | 7.3 |
| Heart failure | 1.8 | 1.4 | 3.0 | 0.7 | 2.5∗ | 1.9 | 2.0 | 1.9 | 1.5 |
| Renal failure | 2.7 | 1.4 | 5.9∗ | 0.7 | 4.1∗ | 2.2 | 4.6∗ | 2.8 | 2.4 |
Description of the study population. Demography, etiology, and outcome of AP. Significantly different values are marked in bold digits with an asterisk. Statistical analysis is summarized in Supplementary Appendix S4.