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. 2019 Sep 26;10(10):718. doi: 10.1038/s41419-019-1957-7

Fig. 8. Model of the mechanisms by which iPSC-MSCs promote colonic mucosal regeneration via TSG-6.

Fig. 8

iPSC-MSC treatment promotes colonic epithelial proliferation to accelerate mucosal healing in mouse models of inflammatory bowel diseases via TSG-6. The effects of iPSC-MSCs is dependent on interactions between hyaluronic acid (HA) and CD44 in an Akt-dependent manner