Table 4.
Risk Factors Associated With Any Liver Event by Cox Proportional Hazards Regression Analysis
| Variable | HR (95% CI) | aHR (95% CI) |
|---|---|---|
| Occult cirrhosis at baseline (yes vs no) | 4.45 (.96–20.62) | 7.12 (1.33–37.99) |
| Overt cirrhosis at baseline (yes vs no) | 8.49 (3.03–23.75) | 8.5 (2.83–25.53) |
| Age (per year) | 1.04 (1.01–1.07) | … |
| Female sex (yes vs no) | 0.79 (.22–2.78) | … |
| Hazardous alcohol intake in the past year (yes vs no) |
2.97 (1.05–8.39) | … |
| BMI ≥30 kg/m2 in past year (yes vs no) | 0.95 (.22–4.17) | … |
| Diabetes in past year (yes vs no) | 1.92 (.61–5.98) | … |
| Lipid-lowering therapy in past year (yes vs no) | 0.46 (.06–3.47) | … |
| Nadir CD4 count (per 100 cells) | 0.79 (.59–1.06) | … |
| Detectable HIV RNA in past year (yes vs no) | 1.71 (.54–5.38) | 1.55 (.51–4.67) |
| HCV coinfection (yes vs no) | 1.83 (.65–5.18) | … |
| HIV duration (per 5 years) | 1.55 (1.23–1.96) | 1.37 (1.09–1.73) |
| ART duration (per 5 years) | 1.63 (1.14–2.32) | … |
Abbreviations: aHR, adjusted hazard ratio; ART, antiretroviral therapy; BMI, body mass index; CI, confidence interval; HCV, hepatitis C virus; HIV, human immunodeficiency virus; HR, hazard ratio.