Table 1.
DHA supplementation modulates phospholipid profile of RAW-ASC cells.
| Fatty acid | Common name | DHA (μM) | ||
|---|---|---|---|---|
| 0 | 10 | 25 | ||
| C14:0 | Myristic acid | 2.94 ± 0.29 | 3.27 ± 0.28 | 4.90 ± 0.84** |
| C16:0 | Palmitic acid | 31.15 ± 3.10 | 31.34 ± 0.79 | 38.59 ± 1.25** |
| C16:1 ω-9 | Palmitoleic acid | 4.67 ± 1.04 | 3.13 ± 0.25 | 2.29 ± 0.50** |
| C18:0 | Stearic acid | 15.60 ± 9.05 | 22.03 ± 0.47 | 18.01 ± 1.21 |
| C18:1 ω-9 | Oleic acid | 36.68 ± 4.32 | 22.23 ± 1.25** | 9.77 ± 0.34** |
| C18:2 ω-6 | Linoleic acid | 0.63 ± 0.88 | 1.26 ± 0.11 | 0.78 ± 0.71 |
| C20:2 ω-6 | Eicosadienoic acid | 4.16 ± 0.92 | 1.13 ± 0.68** | 0.00 ± 0.00** |
| C20:4 ω-6 | Arachidonic acid | 3.27 ± 0.67 | 2.30 ± 0.47 | 1.80 ± 1.15 |
| C20:5 ω-3 | Eicosapentaenoic acid | 0.00 ± 0.00 | 0.00 ± 0.00 | 1.13 ± 0.71 |
| C22:4 ω-6 | Adrenic acid | 0.00 ± 0.00 | 0.15 ± 0.33 | 0.35 ± 0.79 |
| C22:5 ω-3 | ω3 docosapentaenoic acid | 0.00 ± 0.00 | 0.17 ± 0.38 | 0.18 ± 0.40 |
| C22:5 ω-6 | ω6 docosapentaenoic acid | 0.00 ± 0.00 | 0.14 ± 0.31 | 0.00 ± 0.00 |
| C22:6 ω-3 | Docosahexaenoic acid | 0.91 ± 0.53 | 12.85 ± 0.49** | 22.20 ± 1.42** |
| Total SFA | 49.70 ± 5.81 | 55.44 ± 2.42* | 60.63 ± 1.06** | |
| Total MUFA | 41.35 ± 5.29 | 25.05 ± 0.87** | 11.88 ± 0.56** | |
| Total ω-6 | 8.05 ± 1.02 | 5.77 ± 0.90* | 3.71 ± 1.04** | |
| Total ω-6 | 0.91 ± 0.53 | 13.73 ± 1.47** | 23.77 ± 1.07** | |
Data shown are mean percent of total FA ± SEM (n = 6 per group) as determined by GLC. FA levels significantly different from control (0 μM DHA) represented by asterisks
(*p <0.05,
**p <0.01).