Table 1.
Univariate Cox regression analyses of clinical and molecular features associated with OS of MB patients. LC/A, large cell/anaplastic; MBEN, medulloblastoma with extensive odularity.
| Variable | HR (95% CI) | P |
|---|---|---|
| mRNAsi | ||
| Increasing mRNAsi | 11.43 (2.79–46.76) | 7.03E‐04 |
| mDNAsi | ||
| Increasing mDNAsi | 0.65 (0.20–2.07) | 0.468 |
| Immune score | ||
| Increasing immune scores | 1.0000 (0.9996–1.0005) | 0.822 |
| Age | ||
| Increasing years | 0.98 (0.96–1.00) | 0.092 |
| Gender | ||
| Male vs female | 1.17 (0.83–1.63) | 0.368 |
| Metastatic status | ||
| Metastatic vs nonmetastatic | 1.65 (1.18–2.30) | 0.004 |
| Subgroup | ||
| SHH vs WNT | 5.26 (1.62–17.05) | 0.006 |
| Group 3 vs WNT | 10.87 (3.38–34.92) | 6.2E‐05 |
| Group 4 vs WNT | 6.02 (1.90–19.11) | 0.002 |
| Histology | ||
| LC/A vs MBEN | 4.23 (1.01–17.82) | 0.049 |
| Desmoplastic vs MBEN | 1.06 (0.24–4.74) | 0.939 |
| Classic vs MBEN | 1.77 (0.43–7.19) | 0.426 |